Gold Electrode Modified with Vanadium Dioxide and Graphene Oxide for Non-Enzymatic Electrochemical Detection of Glucose
DOI:
https://doi.org/10.32628/IJSRST2613114Keywords:
glucose sensor, non-enzymatic detection, vanadium dioxide, graphene oxide, modified electrodeAbstract
This work presents the development of a non-enzymatic glucose sensor based on a gold electrode modified with a composite of vanadium dioxide (VO2) and graphene oxide (GO). The VO2 was synthesized via a facile hydrothermal method and combined with GO to form a thin film on the Au electrode surface. The electrochemical behavior of the Au/VO2-GO electrode was thoroughly investigated. The modified electrode exhibited a pH sensitivity of 58.0 ± 0.02 mV/pH, closely approximating the theoretical Nernstian response. The electrocatalytic activity towards glucose oxidation was assessed using cyclic voltammetry and square-wave voltammetry in synthetic urine. The anodic peak current increased linearly with glucose concentration in the range of 4.0 to 5.4 mmol.L⁻¹. The sensor demonstrated a detection limit of 0.65 mmol L⁻¹ and a quantification limit of 2.15 mmol.L⁻¹. The electrochemical process was identified as diffusion-controlled. Despite a relatively low electroactive surface area (roughness factor = 1.3 × 10-3), the Au/VO2-GO electrode showed promising sensitivity and stability for non-enzymatic glucose detection, suggesting potential for application in clinical analysis.
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